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PHARMACEUTICAL LIBRARY

Vasodilators

Indirect vasodilators – inhibition of exogenous vasoconstrictio

  • Alfa-beta non-selective antagonists (carvedilol, labetolol etc.)
  • Angiotensin converting enzymes inhibitors “ACE inhibitors”  (captopril, enalapril, lisinopril etc.)
  • Angiotensin-II type 1 receptors inhibitors (losartan, candesartan, valsartan etc.)
  • Alfa 1-2 adrenergic receptors selective agonists
  • Centrally acting drugs (metyldopa, clonidine etc.)

Direct vasodilators – acting from inside the vessels

  • Nitric oxide (NO)
  • Venous vasodilators (nitroglycerine)
  • Venous-arterial vasodilators (nitroprusside)
  • Arterial vasodilators (minidoxil, hydralazide, fenoldopam)

Vasoconstrictors

  • Bosentan – “endothelin antagonist”
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