ROTFEL

PHARMACEUTICAL LIBRARY

Anti-hypertensive drugs

Hypertension first line treatments

Class IV antiarrhytmics – Calcium channels blockers

  • Verapamil (phenylalkylamines)
  • Diltiazem (benzothiazepine)
  • Nifedipine (1,4-dihidropirimidine)

Renin-aldosteron-angiotensin inhibitors (RAAS inhibitors)

Compounds that decrese RAAS action

Angiotensing-converting-enzyme inhibitors (ACE inhibitors)

  • Captopril
  • Enalapril
  • Lisinopril

Angiotensin-II receptor-1 inhibitors

  • Losartan
  • Candesartan
  • Valsartan (for heart failure treatment)

Diuretics

Thiazide diuretics

  • Hydrochlorothiazide
  • Chlorothhiazide

Loop diuretics

  • Furosemide

Vasodilators

Arterial vasodilators

  • Hydralazyne
  • Minoxidil
  • Diazoxide
  • Fenoldopam

Arterial and venous vasodilators

  • Sodium nitroprusside

Antiadrenergics

  • alpha blockers TimPiProna lol
  • beta blockers AndarE lol
  • alfa-beta blochers CaLab lol

Hypertensive crisis emergency management – second line treatments

  • Alpha agonists (ABCG)
  • Esmolol (beta-1 adrenergic receptors selective antagonists) – “beta blockers”
  • Labetalol (alpha-1, beta-1,2 non-selective antagonists) alfa-beta blockers
  • Fenoldopam
  • Nifedipine (CBBs)
  • Nitroprusside
  • Nitroglyceryn (potent vasodilator)
  • Minoxidil (arterial vasodilator)
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