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PHARMACEUTICAL LIBRARY

Antidepressant drugs

ANTIDEPRESSANTS

I generation of antidepressants (1957-1970)

Monoamine oxidase inhibitors (MAOI)

Ist generation – irreversible and non selective MAOI

IInd generation irreversible and selective MAOI

IIIrd generation reversible and selective MAOI

Catechol-O methyl transferase inhibitors (COMTI)

Tricyclic antidepressants (Thymoleptics)

II generation of antidepressants (1970- 2000)

Selective serotonine reuptake inhibitors (SSRI)

III generation of antidepressants

Norepinephrine reuptake inhibitors (NRI)

Serotonin/norepinephrine reuptake inhibitors (SNRI)

Norepinephrine/serotonine specific antidepressants (NSSA)

Other antidepressants

Serotonin precursors

Serotonine agents

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