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Antidepressant drugs
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ANTIDEPRESSANTS
I generation of antidepressants (1957-1970)
Monoamine oxidase inhibitors (MAOI)
Ist generation – irreversible and non selective MAOI
IInd generation irreversible and selective MAOI
IIIrd generation reversible and selective MAOI
Catechol-O methyl transferase inhibitors (COMTI)
Tricyclic antidepressants (Thymoleptics)
II generation of antidepressants (1970- 2000)
Selective serotonine reuptake inhibitors (SSRI)
III generation of antidepressants
Norepinephrine reuptake inhibitors (NRI)
Serotonin/norepinephrine reuptake inhibitors (SNRI)
Norepinephrine/serotonine specific antidepressants (NSSA)
Other antidepressants
Serotonin precursors
Serotonine agents