RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM INHIBITORS

The RAAS inhibitors are only one class of antihypertensive drugs and are classified as shown below. RAAS are subdivided into ACE inhibitors, ANGII receptor antagonists and Renin inhibitors.

Angiotensin Converting Enzyme inhibitors (ACE inhibitors)

Sulfhydryl containing ACE inhibitors

• Zofenopril
• Captopril

Carboxylate containing ACE inhibitors

• Enalapril (prodrug of enalaprilat)
• Enalaprilat
• Lisinopril
• Cliazapril
• Benazepril
• Imidapril
• Spirapril
• Idrapril
• Moexipril
• Trandolapril

Phosphinate containing ACE inhibitors

• Fosinopril (prodrug of fosinoprilat)
• Fosinoprilat

Phosphonate containing ACE inhibitors

• Ceronapril

Angiotensin II receptor antagonists (ANGII receptor antagonists)

• Losartan
• Valsartan
• Irbesartan
• Candesartan
• Candesartan cliexetil
• Eprosartan

Renin Inhibitors

• Angiotensinogen
• Zankiren
• Ciprokiren
• Remikiren
• Terlakiren