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PHARMACEUTICAL LIBRARY

Antiarrhythmic drugs

CLASSES OF ANTIARRHYTHMIC DRUGS

Class I Antiarrhythmics – Na+channel blockers

Subclass IA – Moderate Na+channel blockers

Subclass IB – Mild Na+channel blockers

  • Lidocaine
  • Mexiletine (oral lidocaine derivative with similar activity)
  • Tocainide (not frequently used because of potential bone marrow suppression)
  • Phenytoin (adinistered as a salt to avoid sedative effects)

Subclass IA – Marked Na+channel blockers

Class II Antiarrhythmics – β-blockers

Class III antiarrhythmics – K+channel blockers

Class IV antiarrhythmics – Ca2+ channel blockers

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